HelixlyAI Genome Report Prepared for Sample Subject
Report ID HX-2026-0042 · synthetic
Traits & Carrier Status · Document 23 of 24

Bone Density

Variants associated with Sample Subject's bone-mineral-density baseline context, across the VDR, COL1A1, and LRP5 loci. All values below are synthetic and for demonstration only.

3 findings 1 Tier 2 2 Tier 3 Reviewed 2026-01-15

Provenance

Data Provenance verified chain
Document
Bone Density
Source assembly
GRCh37 (hg19)
Source file SHA-256
0000a1b2c3d4e5f6…4b5c6d7e
Supersedes
prior v1 · SHA 1111f0e9…
Evidence sources
PubMed, dbSNP, GWAS Catalog
Access date
2026-01-15

Per-Gene Findings

Filter:

VDR — BsmI Site Heterozygous

Vitamin D receptor · bone-mineral-density marker
PubMedTier 2
rs1544410 12:48,239,835 GA

rs1544410 is G/A — the VDR BsmI site, heterozygous in this sample. This VDR intronic marker associates with bone-mineral-density variation in the cited literature.

Source: PubMed PMID 18348749 ↗ · dbSNP rs1544410 ↗

COL1A1 — Sp1 Site Heterozygous

Collagen type I alpha 1 · Sp1 binding site
dbSNPTier 3
rs1800012 17:48,278,415 GT

rs1800012 is G/T at the COL1A1 Sp1 site. This sample carries one copy of the T (Sp1 minor) allele. dbSNP records this variant's identifier and GRCh37 position.

Source: dbSNP rs1800012 ↗

LRP5 — A1330V Allele Present

LDL receptor-related protein 5 · bone-mass locus
GWAS CatalogTier 3
rs3736228 11:68,207,310 CT

rs3736228 is C/T — one copy of the LRP5 A1330V allele. The GWAS Catalog records bone-mineral-density associations at the LRP5 locus.

Source: GWAS Catalog LRP5 ↗

Genotype Table

Variants evaluated in this document — synthetic
rsIDchr:posGenotypeGeneSignificance
rs154441012:48,239,835GAVDRTier 2
rs180001217:48,278,415GTCOL1A1Tier 3
rs373622811:68,207,310CTLRP5Tier 3
Consult your prescribing clinician. This HelixlyAI report is a synthetic demonstration generated from a consumer DNA export. It is not a diagnosis, prescription, or substitute for professional medical advice. Do not start, stop, or change any treatment based on this document. Genotype is one of many factors influencing bone-mineral density.